Paired Box 3 antibody (AA 142-203)

Catalog No. ABIN1724816

Product Details anti-Paired Box 3 Antibody

Target: Paired Box 3 (PAX3)

Binding Specificity: AA 142-203

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Paired Box 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: PAX3 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human PAX3 (AA: 142-203) expressed in E. Coli.

Clone: 7D8G7

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-Paired Box 3 antibody (ABIN1724816)

Dong, Li, Cao, Liu, Pier, Chen, Xu, Chen, Wang, Cui: "FGF2 regulates melanocytes viability through the STAT3-transactivated PAX3 transcription." in: Cell death and differentiation, Vol. 19, Issue 4, pp. 616-22, (2012) (PubMed).

Target Details for Paired Box 3

Target: Paired Box 3 (PAX3)

Alternative Name: PAX3 (PAX3 Products)

Synonyms: PAX3 antibody, cdhs antibody, hup2 antibody, pax-3 antibody, ws1 antibody, xpax3 antibody, Pax3 antibody, pax3 antibody, pax3b antibody, xPax3-B antibody, CDHS antibody, HUP2 antibody, WS1 antibody, WS3 antibody, Pax-3 antibody, Sp antibody, splotch antibody, zgc:92547 antibody, paired box 3 antibody, paired box 3 L homeolog antibody, paired box 3a antibody, PAX3 antibody, pax3 antibody, pax3.L antibody, Pax3 antibody, pax3a antibody

Background:

Description: This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

Aliases: WS1, WS3, CDHS, HUP2

Molecular Weight: 53kDa

Gene ID: 5077

HGNC: 5077

UniProt: P23760

Pathways: Sensory Perception of Sound, Tube Formation