Nucleostemin antibody (AA 1-226)
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- Target See all Nucleostemin (GNL3) Antibodies
- Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))
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Binding Specificity
- AA 1-226
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Nucleostemin antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Purpose
- GNL3 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human GNL3 (AA: 1-226) expressed in E. Coli.
- Clone
- 2C8D5
- Isotype
- IgG1
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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GNL3L depletion destabilizes MDM2 and induces p53-dependent G2/M arrest." in: Oncogene, Vol. 30, Issue 14, pp. 1716-26, (2011) (PubMed).
: "
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GNL3L depletion destabilizes MDM2 and induces p53-dependent G2/M arrest." in: Oncogene, Vol. 30, Issue 14, pp. 1716-26, (2011) (PubMed).
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- Target
- Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))
- Alternative Name
- GNL3 (GNL3 Products)
- Background
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Description: The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene.
Aliases: NS, E2IG3, NNP47, C77032
- Molecular Weight
- 62kDa
- Gene ID
- 26354
- HGNC
- 26354
- UniProt
- Q9BVP2
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