MAP1LC3A antibody (AA 1-121)

Catalog No. ABIN1724768

Product Details anti-MAP1LC3A Antibody

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Binding Specificity: AA 1-121

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAP1LC3A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purpose: MAP1LC3A Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human MAP1LC3A (AA: 1-121) expressed in E. Coli.

Clone: 5B10D8

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-MAP1LC3A antibody (ABIN1724768)

Jiang, Shao, Wang, Yan, Liu: "Decreased expression of Beclin-1 and LC3 in human lung cancer." in: Molecular biology reports, Vol. 39, Issue 1, pp. 259-67, (2011) (PubMed).

Han, Sun, Wang, Cai, Lou, Sun, Zhao: "Overexpression of microtubule-associated protein-1 light chain 3 is associated with melanoma metastasis and vasculogenic mimicry." in: The Tohoku journal of experimental medicine, Vol. 223, Issue 4, pp. 243-51, (2011) (PubMed).

Target Details for MAP1LC3A

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Alternative Name: MAP1LC3A (MAP1LC3A Products)

Synonyms: ATG8E antibody, LC3 antibody, LC3A antibody, MAP1ALC3 antibody, MAP1BLC3 antibody, 1010001H21Rik antibody, 4922501H04Rik antibody, LC3a antibody, MGC69006 antibody, zgc:77094 antibody, MGC89867 antibody, MAP1LC3A antibody, map1lc3a antibody, microtubule associated protein 1 light chain 3 alpha antibody, microtubule-associated protein 1 light chain 3 alpha antibody, microtubule associated protein 1 light chain 3 alpha S homeolog antibody, MAP1LC3A antibody, Map1lc3a antibody, map1lc3a.S antibody, map1lc3a antibody

Background:

Description: MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.

Aliases: LC3, LC3A, ATG8E, MAP1ALC3, MAP1BLC3

Molecular Weight: 14.3kDa

Gene ID: 84557

HGNC: 84557

UniProt: Q9H492

Pathways: Autophagy