CBX8 antibody (AA 17-222)
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- Target See all CBX8 Antibodies
- CBX8 (Chromobox Homolog 8 (CBX8))
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Binding Specificity
- AA 17-222
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CBX8 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human CBX8 (AA: 17-222) expressed in E. coli.
- Clone
- 9C3D4
- Isotype
- IgG1
- Top Product
- Discover our top product CBX8 Primary Antibody
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus." in: The EMBO journal, Vol. 26, Issue 6, pp. 1637-48, (2007) (PubMed).
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Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus." in: The EMBO journal, Vol. 26, Issue 6, pp. 1637-48, (2007) (PubMed).
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- Target
- CBX8 (Chromobox Homolog 8 (CBX8))
- Alternative Name
- CBX8 (CBX8 Products)
- Synonyms
- cbx8 antibody, MGC147589 antibody, Pc3 antibody, PC3 antibody, RC1 antibody, chromobox 8 antibody, chromobox 8 S homeolog antibody, chromobox homolog 8a (Pc class homolog, Drosophila) antibody, cbx8 antibody, CBX8 antibody, Cbx8 antibody, cbx8.S antibody, cbx8a antibody
- Background
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Description: Chromobox homolog 8 (CBX8), a Polycomb Group protein that interacts with MLL-AF9 and TIP60, plays an essential role in MLL-AF9 transcriptional regulation and leukemogenesis. CBX8, which is part of one of the PRC1 complexes, regulates proliferation of diploid human and mouse fibroblasts through direct binding to the INK4A-ARF locus. , ,
Aliases: PC3, RC1
- Molecular Weight
- 43.4 kDa
- Gene ID
- 57332
- HGNC
- 57332
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