CBX8 antibody (AA 17-222)
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- Target See all CBX8 Antibodies
- CBX8 (Chromobox Homolog 8 (CBX8))
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Binding Specificity
- AA 17-222
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CBX8 antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- CBX8 Antibody
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human CBX8 (AA: 17-222 ) expressed in E. Coli.
- Clone
- 9C3D4
- Isotype
- IgG2b
- Top Product
- Discover our top product CBX8 Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus." in: The EMBO journal, Vol. 26, Issue 6, pp. 1637-48, (2007) (PubMed).
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Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus." in: The EMBO journal, Vol. 26, Issue 6, pp. 1637-48, (2007) (PubMed).
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- Target
- CBX8 (Chromobox Homolog 8 (CBX8))
- Alternative Name
- CBX8 (CBX8 Products)
- Synonyms
- cbx8 antibody, MGC147589 antibody, Pc3 antibody, PC3 antibody, RC1 antibody, chromobox 8 antibody, chromobox 8 S homeolog antibody, chromobox homolog 8a (Pc class homolog, Drosophila) antibody, cbx8 antibody, CBX8 antibody, Cbx8 antibody, cbx8.S antibody, cbx8a antibody
- Background
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Description: Chromobox homolog 8 (CBX8), a Polycomb Group protein that interacts with MLL-AF9 and TIP60, plays an essential role in MLL-AF9 transcriptional regulation and leukemogenesis. CBX8, which is part of one of the PRC1 complexes, regulates proliferation of diploid human and mouse fibroblasts through direct binding to the INK4A-ARF locus.
Aliases: PC3, RC1
- Molecular Weight
- 43.4kDa
- Gene ID
- 57332
- HGNC
- 57332
- UniProt
- Q9HC52
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