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BMPR1A antibody (AA 179-378)

BMPR1A Reactivity: Human, Mouse WB, ELISA, IHC, FACS, ICC Host: Mouse Monoclonal 4B7B2 unconjugated
Catalog No. ABIN1724745
  • Target See all BMPR1A Antibodies
    BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
    Binding Specificity
    • 16
    • 10
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 179-378
    Reactivity
    • 74
    • 51
    • 32
    • 1
    Human, Mouse
    Host
    • 90
    • 6
    • 1
    Mouse
    Clonality
    • 92
    • 5
    Monoclonal
    Conjugate
    • 42
    • 9
    • 8
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BMPR1A antibody is un-conjugated
    Application
    • 86
    • 57
    • 32
    • 23
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human BMPR1A (AA: 179-378 ) expressed in E. coli.
    Clone
    4B7B2
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Nickel, Kotzsch, Sebald, Mueller: "Purification, crystallization and preliminary data analysis of the ligand-receptor complex of the growth and differentiation factor 5 variant R57A (GDF5R57A) and BMP receptor IA (BRIA)." in: Acta crystallographica. Section F, Structural biology and crystallization communications, Vol. 67, Issue Pt 5, pp. 551-5, (2011) (PubMed).

    Nieminen, Abdel-Rahman, Ristimäki, Lappalainen, Lahermo, Mecklin, Järvinen, Peltomäki: "BMPR1A mutations in hereditary nonpolyposis colorectal cancer without mismatch repair deficiency." in: Gastroenterology, Vol. 141, Issue 1, pp. e23-6, (2011) (PubMed).

  • Target
    BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
    Alternative Name
    BMPR1A (BMPR1A Products)
    Synonyms
    10q23del antibody, ACVRLK3 antibody, ALK3 antibody, CD292 antibody, SKR5 antibody, 1110037I22Rik antibody, AU045487 antibody, BMPR-IA antibody, Bmpr antibody, BMPR-1 antibody, BRK-1 antibody, BMPR1A antibody, acvrlk3 antibody, alk-3 antibody, alk3 antibody, cd292 antibody, skr5 antibody, BR1a antibody, alk3tr antibody, bmpr1a antibody, zgc:136731 antibody, wu:fe05b06 antibody, wu:fe06e10 antibody, zgc:92227 antibody, bone morphogenetic protein receptor type 1A antibody, bone morphogenetic protein receptor, type 1A antibody, bone morphogenetic protein receptor type 1A S homeolog antibody, bone morphogenetic protein receptor, type IAa antibody, bone morphogenetic protein receptor, type IAb antibody, BMPR1A antibody, Bmpr1a antibody, bmpr1a antibody, bmpr1a.S antibody, bmpr1aa antibody, bmpr1ab antibody
    Background

    Description: The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. , ,

    Aliases: ALK3, SKR5, CD292, ACVRLK3, 10q23del

    Molecular Weight
    60 kDa
    Gene ID
    657
    HGNC
    657
    Pathways
    Stem Cell Maintenance
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