GLUT4 antibody (AA 224-353)
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- Target See all GLUT4 (SLC2A4) Antibodies
- GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))
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Binding Specificity
- AA 224-353
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This GLUT4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human SLC2A4 (AA: 224-353 ) expressed in E. coli.
- Clone
- 3G10A3
- Isotype
- IgG2b
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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Insulin-stimulated GLUT4 protein translocation in adipocytes requires the Rab10 guanine nucleotide exchange factor Dennd4C." in: The Journal of biological chemistry, Vol. 286, Issue 19, pp. 16541-5, (2011) (PubMed).
: "
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Insulin-stimulated GLUT4 protein translocation in adipocytes requires the Rab10 guanine nucleotide exchange factor Dennd4C." in: The Journal of biological chemistry, Vol. 286, Issue 19, pp. 16541-5, (2011) (PubMed).
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- Target
- GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))
- Alternative Name
- SLC2A4 (SLC2A4 Products)
- Synonyms
- GLUT4 antibody, Glut-4 antibody, Glut4 antibody, glut4 antibody, slc2a4 antibody, SLC2A4 antibody, solute carrier family 2 member 4 antibody, solute carrier family 2 (facilitated glucose transporter), member 4 antibody, solute carrier family 2 (facilitated glucose transporter), member 4 L homeolog antibody, SLC2A4 antibody, Slc2a4 antibody, GLUT4 antibody, slc2a4.L antibody
- Background
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Description: This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). , , ,
Aliases: GLUT4
- Molecular Weight
- 54.8 kDa
- Gene ID
- 6517
- HGNC
- 6517
- Pathways
- AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, Warburg Effect
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