PARP1 antibody
(1 reference)-
- Target See all PARP1 Antibodies
- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PARP1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Purpose
- PARP Antibody
- Purification
- Ascitic fluid
- Immunogen
- Synthetic peptide of human PARP, conjugated to KLH.
- Clone
- 7A10
- Isotype
- IgG1
- Top Product
- Discover our top product PARP1 Primary Antibody
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anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibody
KO Validated PARP1 Reactivity: Human WB, IP, IF, IHC (p), ICC, ChIP Host: Rabbit Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 81-390) antibodyPARP1 Reactivity: Human WB, IHC, IP, IF Host: Rabbit Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 661-881) antibodyPARP1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 201-300) antibodyPARP1 Reactivity: Human, Mouse, Rat, Chicken WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (C-Term) antibodyPARP1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100) antibodyPARP1 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 3G4 unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 670-858) antibodyPARP1 Reactivity: Human, Mouse, Rat WB, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibodyPARP1 Reactivity: Human WB, ELISA, IHC, FACS, IF Host: Rabbit Monoclonal 8C7 unconjugated Recombinant Antibody
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (cleaved) antibodyPARP1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 183-214) antibodyPARP1 Reactivity: Human WB, ELISA, FACS, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function." in: The Journal of biological chemistry, Vol. 276, Issue 49, pp. 45588-97, (2001) (PubMed).
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: "The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function." in: The Journal of biological chemistry, Vol. 276, Issue 49, pp. 45588-97, (2001) (PubMed).
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- Target
- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
- Alternative Name
- PARP (PARP1 Products)
- Background
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Description: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Aliases: PARP, PPOL, ADPRT, ADPRT1, PARP-1, pADPRT-1, PARP1
- Molecular Weight
- 117kDa
- Gene ID
- 142
- HGNC
- 142
- UniProt
- P09874
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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