DKK3 antibody

Catalog No. ABIN1724727

Product Details anti-DKK3 Antibody

Target: DKK3

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DKK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purpose: DKK3 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human DKK3 expressed in E. Coli.

Clone: 4G7

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-DKK3 antibody (ABIN1724727)

Pei, Kano, Iijima, Morishita, Inadome, Noguchi: "Overexpression of Dickkopf 3 in hepatoblastomas and hepatocellular carcinomas." in: Virchows Archiv : an international journal of pathology, Vol. 454, Issue 6, pp. 639-46, (2009) (PubMed).

Kurose, Sakaguchi, Nasu, Ebara, Kaku, Kariyama, Arao, Miyazaki, Tsushima, Namba, Kumon, Huh: "Decreased expression of REIC/Dkk-3 in human renal clear cell carcinoma." in: The Journal of urology, Vol. 171, Issue 3, pp. 1314-8, (2004) (PubMed).

Persson, Rosenquist, Sommarin: "Identification of a novel calreticulin isoform (Crt2) in human and mouse." in: Gene, Vol. 297, Issue 1-2, pp. 151-8, (2002) (PubMed).

Target Details for DKK3

Target: DKK3

Abstract: DKK3 Products

Synonyms: REIC antibody, RIG antibody, reic antibody, dkk-3 antibody, AW061014 antibody, C87148 antibody, Reic antibody, p29 antibody, dickkopf WNT signaling pathway inhibitor 3 antibody, dickkopf WNT signaling pathway inhibitor 3 S homeolog antibody, DKK3 antibody, dkk3 antibody, dkk3.S antibody, Dkk3 antibody

Background:

Description: Dkk-3 (Dickkopf-3) is a member of the dickkopf family. It is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.

Aliases: RIG, REIC

Molecular Weight: 38kDa

Gene ID: 27122

HGNC: 27122

UniProt: Q9UBP4