EPH Receptor B4 antibody (AA 562-612)

Catalog No. ABIN1724713

Product Details anti-EPH Receptor B4 Antibody

Target: EPH Receptor B4 (EPHB4)

Binding Specificity: AA 562-612

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor B4 antibody is un-conjugated

Application: ELISA

Purpose: EphB4 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of EphB4 (aa562-612)expressed in E. Coli.

Clone: 7H4A6

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-EPH Receptor B4 antibody (ABIN1724713)

Red-Horse, Kapidzic, Zhou, Feng, Singh, Fisher: "EPHB4 regulates chemokine-evoked trophoblast responses: a mechanism for incorporating the human placenta into the maternal circulation." in: Development (Cambridge, England), Vol. 132, Issue 18, pp. 4097-106, (2005) (PubMed).

Xia, Kumar, Masood, Zhu, Reddy, Krasnoperov, Quinn, Henshall, Sutherland, Pinski, Daneshmand, Buscarini, Stein, Zhong, Broek, Roy-Burman, Gill: "EphB4 expression and biological significance in prostate cancer." in: Cancer research, Vol. 65, Issue 11, pp. 4623-32, (2005) (PubMed).

Jiménez-Vega, Yepiz-Plascencia, Söderhäll, Vargas-Albores: "A single WAP domain-containing protein from Litopenaeus vannamei hemocytes." in: Biochemical and biophysical research communications, Vol. 314, Issue 3, pp. 681-7, (2004) (PubMed).

Target Details for EPH Receptor B4

Target: EPH Receptor B4 (EPHB4)

Alternative Name: EphB4 (EPHB4 Products)

Synonyms: HTK antibody, MYK1 antibody, TYRO11 antibody, htk antibody, myk1 antibody, ephB4a antibody, tyro11 antibody, ephb4b antibody, MGC130997 antibody, AI042935 antibody, Htk antibody, MDK2 antibody, Myk1 antibody, Tyro11 antibody, cb646 antibody, ephB4 antibody, rtk5 antibody, EphB-rtk8 antibody, cb417 antibody, rtk8 antibody, EPH receptor B4 antibody, EPH receptor B4 L homeolog antibody, EPH receptor B4 S homeolog antibody, Eph receptor B4 antibody, eph receptor B4a antibody, eph receptor B4b antibody, EPHB4 antibody, ephb4.L antibody, ephb4.S antibody, ephb4 antibody, Ephb4 antibody, ephb4a antibody, ephb4b antibody

Background:

Description: EphB4: EPH receptor B4. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.

Aliases: HTK, MYK1, TYRO11

Molecular Weight: 108kDa

Gene ID: 2050

HGNC: 2050

UniProt: P54760

Pathways: RTK Signaling