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ITK antibody (AA 2-110)

ITK Reactivity: Human WB, ELISA Host: Mouse Monoclonal 5G12C4 unconjugated
Catalog No. ABIN1724708
  • Target See all ITK Antibodies
    ITK (IL2-Inducible T-Cell Kinase (ITK))
    Binding Specificity
    • 14
    • 10
    • 9
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-110
    Reactivity
    • 48
    • 19
    • 12
    • 6
    • 3
    Human
    Host
    • 62
    • 3
    • 2
    Mouse
    Clonality
    • 64
    • 3
    Monoclonal
    Conjugate
    • 28
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITK antibody is un-conjugated
    Application
    • 40
    • 35
    • 14
    • 14
    • 11
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA
    Purification
    purified
    Immunogen
    Purified recombinant fragment of ITK (aa2-110) expressed in E. coli.
    Clone
    5G12C4
    Isotype
    IgG1
    Top Product
    Discover our top product ITK Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Graves, Siroux, Guerra, Klimecki, Martinez: "Association of atopy and eczema with polymorphisms in T-cell immunoglobulin domain and mucin domain-IL-2-inducible T-cell kinase gene cluster in chromosome 5 q 33." in: The Journal of allergy and clinical immunology, Vol. 116, Issue 3, pp. 650-6, (2005) (PubMed).

    Perez-Villar, ODay, Hewgill, Nadler, Kanner: "Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin alpha (Rch1alpha)." in: International immunology, Vol. 13, Issue 10, pp. 1265-74, (2001) (PubMed).

  • Target
    ITK (IL2-Inducible T-Cell Kinase (ITK))
    Alternative Name
    ITK (ITK Products)
    Synonyms
    Emt antibody, Tcsk antibody, Tsk antibody, EMT antibody, LPFS1 antibody, LYK antibody, PSCTK2 antibody, IL2 inducible T cell kinase antibody, IL2 inducible T-cell kinase antibody, IL2-inducible T-cell kinase antibody, Itk antibody, ITK antibody
    Background

    Description: ITK: IL2-inducible T-cell kinase. This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.

    Aliases: EMT, LYK, PSCTK2

    Gene ID
    3702
    HGNC
    3702
    Pathways
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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