YES1 antibody (AA 10-193)

Catalog No. ABIN1724691

Product Details anti-YES1 Antibody

Target: YES1 (V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1))

Binding Specificity: AA 10-193

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This YES1 antibody is un-conjugated

Application: ELISA

Purpose: YES1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of YES (aa10-193) expressed in E. Coli.

Clone: 2F3E6

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-YES1 antibody (ABIN1724691)

Rush, Moritz, Lee, Guo, Goss, Spek, Zhang, Zha, Polakiewicz, Comb: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, (2005) (PubMed).

Reinehr, Becker, Höngen, Haüssinger: "The Src family kinase Yes triggers hyperosmotic activation of the epidermal growth factor receptor and CD95." in: The Journal of biological chemistry, Vol. 279, Issue 23, pp. 23977-87, (2004) (PubMed).

Annerén, Cowan, Melton: "The Src family of tyrosine kinases is important for embryonic stem cell self-renewal." in: The Journal of biological chemistry, Vol. 279, Issue 30, pp. 31590-8, (2004) (PubMed).

Target Details for YES1

Target: YES1 (V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1))

Alternative Name: YES1 (YES1 Products)

Synonyms: HsT441 antibody, P61-YES antibody, Yes antibody, c-yes antibody, yes antibody, p61-Yes antibody, hst441 antibody, p61-yes antibody, YES antibody, c-Yes antibody, p60c-yes antibody, YES proto-oncogene 1, Src family tyrosine kinase antibody, YES proto-oncogene 1, Src family tyrosine kinase L homeolog antibody, YES1 antibody, yes1.L antibody, yes1 antibody, Yes1 antibody

Background:

Description: YES1, v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1. This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22.

Aliases: Yes, c-yes, HsT441, P61-YES, YES1

Gene ID: 7525

HGNC: 7525

UniProt: P07947

Pathways: CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling