CSNK1A1 antibody

Catalog No. ABIN1724653

Product Details anti-CSNK1A1 Antibody

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CSNK1A1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purpose: CK1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of CK1 expressed in E. Coli.

Clone: 3C10F7

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CSNK1A1

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Alternative Name: CK1 (CSNK1A1 Products)

Background:

Description: CK1 (also designated Cytokeratin 1 or KRT1 ),with 644-amino acid protein (about 70 kDa), is a member of the keratin family. Cytokeratins play a critical role in differentiation and tissue specialization, and they function to maintain the overall structural integrity of epithelial cells.CK1 consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. CK1 is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.

Aliases: K1, CK1, EHK, EHK1, EPPK, KRT1A, NEPPK

Gene ID: 3848

HGNC: 3848

UniProt: P04264

Pathways: WNT Signaling, Hedgehog Signaling