IL1A antibody

Catalog No. ABIN1724632

Product Details anti-IL1A Antibody

Target: IL1A (Interleukin 1 alpha (IL1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: purified

Immunogen: Purified recombinant fragment of human IL1a expressed in E. coli.

Clone: 3A6F11

Isotype: IgG2a

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-IL1A antibody (ABIN1724632)

Grimaldi, Casadei, Ferri, Veglia, Licastro, Annoni, Biunno, De Bellis, Sorbi, Mariani, Canal, Griffin, Franceschi: "Association of early-onset Alzheimer's disease with an interleukin-1alpha gene polymorphism." in: Annals of neurology, Vol. 47, Issue 3, pp. 361-5, (2000) (PubMed).

Du, Dodel, Eastwood, Bales, Gao, Lohmüller, Müller, Kurz, Zimmer, Evans, Hake, Gasser, Oertel, Griffin, Paul, Farlow: "Association of an interleukin 1 alpha polymorphism with Alzheimer's disease." in: Neurology, Vol. 55, Issue 4, pp. 480-3, (2000) (PubMed).

Target Details for IL1A

Target: IL1A (Interleukin 1 alpha (IL1A))

Alternative Name: IL-1a (IL1A Products)

Synonyms: IL-1A antibody, IL1 antibody, IL1-ALPHA antibody, IL1F1 antibody, IL-6 antibody, Il-1a antibody, IL-1 alpha antibody, IL-1alpha antibody, L1A antibody, interleukin 1 alpha antibody, interleukin 6 antibody, IL1A antibody, IL6 antibody, Il1a antibody

Background:

Description: Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease

Aliases: IL1, IL-1A, IL1F1, IL1-ALPHA

Molecular Weight: 30.6 kDa

Gene ID: 3552

HGNC: 3552

Pathways: NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints