Claudin 9 antibody

Catalog No. ABIN1720917

Product Details anti-Claudin 9 Antibody

Target: Claudin 9 (CLDN9)

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This Claudin 9 antibody is un-conjugated

Application: Cell-ELISA (cELISA), Flow Cytometry (FACS)

Specificity: Anti-human Claudin 9

Characteristics: Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells

Purification: Protein G

Immunogen: genetic immunisation with cDNA encoding human Claudin 9

Clone: YD-4E9

Isotype: IgG2b

Application Details

Application Notes: Flow cytometry: 1.2 µg/10^6 cells
ELISA: 1:200 - 1:400
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Comment:

Synonyms: CLDN9

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C

Storage Comment: short term: 2 °C - 8 °C, long term: -20 °C

References for anti-Claudin 9 antibody (ABIN1720917)

Fofana, Zona, Thumann, Heydmann, Durand, Lupberger, Blum, Pessaux, Gondeau, Reynolds, McKeating, Grunert, Thompson, Zeisel, Baumert: "Functional analysis of claudin-6 and claudin-9 as entry factors for hepatitis C virus infection of human hepatocytes by using monoclonal antibodies." in: Journal of virology, Vol. 87, Issue 18, pp. 10405-10, (2013) (PubMed).

Target Details for Claudin 9

Target: Claudin 9 (CLDN9)

Alternative Name: CLAUDIN9 (CLDN9 Products)

Synonyms: CLDN9 antibody, nmf329 antibody, claudin 9 antibody, CLDN9 antibody, Cldn9 antibody

Background: Claudin 9 plays a major role in tight junction-specific obliteration of the intercellular space. Claudin 6 and Claudin 9 have been reported to mediate HCV entry

UniProt: O95484

Pathways: Cell-Cell Junction Organization, Hepatitis C