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GORASP2 antibody (AA 151-250)

GORASP2 Reactivity: Mouse, Xenopus laevis WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1715031
  • Target See all GORASP2 Antibodies
    GORASP2 (Golgi Reassembly Stacking Protein 2, 55kDa (GORASP2))
    Binding Specificity
    • 14
    • 10
    • 8
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    Reactivity
    • 47
    • 28
    • 15
    • 14
    • 1
    • 1
    • 1
    Mouse, Xenopus laevis
    Host
    • 59
    • 3
    Rabbit
    Clonality
    • 62
    Polyclonal
    Conjugate
    • 26
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GORASP2 antibody is un-conjugated
    Application
    • 47
    • 23
    • 12
    • 12
    • 9
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Mouse, Xenopus laevis
    Predicted Reactivity
    Human,Rat,Cow,Sheep,Pig,Horse,Rabbit,Zebrafish
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Golgi phosphoprotein 6
    Isotype
    IgG
    Top Product
    Discover our top product GORASP2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    GORASP2 (Golgi Reassembly Stacking Protein 2, 55kDa (GORASP2))
    Alternative Name
    Golgi phosphoprotein 6 (GORASP2 Products)
    Synonyms
    MGC53281 antibody, MGC132131 antibody, MGC73072 antibody, zgc:73072 antibody, DKFZp459O1715 antibody, 0610011A07Rik antibody, 2410043M02Rik antibody, 5730520M13Rik antibody, 9430094F20Rik antibody, AW552058 antibody, GOLPH2 antibody, GRASP55 antibody, GRS2 antibody, p59 antibody, Grs2 antibody, GOLPH6 antibody, golgi reassembly stacking protein 2 L homeolog antibody, golgi reassembly stacking protein 2 antibody, gorasp2.L antibody, gorasp2 antibody, GORASP2 antibody, CC1G_02936 antibody, Gorasp2 antibody
    Background

    Synonyms: Golgi phosphoprotein 6, Golgi reassembly stacking protein 2, Golgi reassembly stacking protein 2, 55 kDa, Golgi reassembly stacking protein of 55 kDa, Golgi reassembly-stacking protein 2, Golgi reassembly-stacking protein of 55 kDa, GOLPH2, GOLPH6, GORASP2, GORS2_HUMAN, GRASP55, GRS2, p59, RP23-428O15.1.

    Background: The Golgi apparatus is a highly complex organelle comprised of a stack of cisternal membranes on the secretory pathway from the ER to the cell surface. The structure is maintained by an exoskeleton or Golgi matrix constructed from a family of coiled-coil protein, the golgins and other peripheral membrane components such as GRASP55 and GRASP65 (1). GRASP55 (Golgi reassembly stacking protien or p59) is a component of the Golgi stacking machinery. GRASP55 is highly homologous to GRASP65 and contains two PDZ domains. GRASP55 is myristoylated and palmitoylated. Unlike GRASP65, GRASP55 does not have detectable binding with the vesicle docking protein GM130 and is located on the medial-Golgi rather than cis-Golgi. Both GRASP55 and GRASP65 function in the stacking of Golgi Cisternae (2,3). The novel coiled-coil protein golgin 45 interacts with GRASP55 and the GTP form of Rab 2, suggesting that GRASP55 and golgin 45 form a Rab 2 effector complex on medial-Golgi essential for normal protein transport and Golgi structure (4). ERK2 directly phosphorylates GRASP55, which is phosphorylated in mitotic cells, suggesting that mitogen-activated protein kinase kinase (MKK)/ERK pathway phosphorylates the Golgi during mitosis (5).

    Gene ID
    26003
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