TMEM242 antibody (AA 21-100)

Catalog No. ABIN1714981

Product Details anti-TMEM242 Antibody

Target: TMEM242 (Transmembrane Protein 242 (TMEM242))

Binding Specificity: AA 21-100

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM242 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C6orf35

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TMEM242 antibody (ABIN1714981)

Morgenstern, Peikert, Lübbert, Suppanz, Klemm, Alka, Steiert, Naumenko, Schendzielorz, Melchionda, Mühlhäuser, Knapp, Busch, Stiller, Dannenmaier, Lindau, Licheva, Eickhorst, Galbusera, Zerbes, Ryan et al.: "Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. ..." in: Cell metabolism, Vol. 33, Issue 12, pp. 2464-2483.e18, (2022) (PubMed).

Target Details for TMEM242

Target: TMEM242 (Transmembrane Protein 242 (TMEM242))

Alternative Name: C6orf35 (TMEM242 Products)

Synonyms: C6orf35 antibody, 1110008A10Rik antibody, 2310046K16Rik antibody, 5730437N04Rik antibody, BM033 antibody, transmembrane protein 242 antibody, TMEM242 antibody, Tmem242 antibody

Background:

Synonyms: BM033, C6orf35, TM242_HUMAN, Chromosome 6 open reading frame 35, UPF0463 transmembrane protein C6orf35.

Background: Making up nearly 6 % of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. The C6orf35 gene product has been provisionally designated C6orf35 pending further characterization.

Gene ID: 729515