SPAG6 antibody (AA 233-290)

Catalog No. ABIN1714878

Product Details anti-SPAG6 Antibody

Target: SPAG6 (Sperm Associated Antigen 6 (SPAG6))

Binding Specificity: AA 233-290

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPAG6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SPAG6

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SPAG6

Target: SPAG6 (Sperm Associated Antigen 6 (SPAG6))

Alternative Name: SPAG6 (SPAG6 Products)

Synonyms: Repro-SA-1 antibody, pf16 antibody, PF16 antibody, RGD1310892 antibody, zgc:91805 antibody, SPAG6 antibody, repro-sa-1 antibody, DKFZp459D035 antibody, sperm associated antigen 6 antibody, sperm associated antigen 6-like antibody, sperm associated antigen 6 L homeolog antibody, SPAG6 antibody, Spag6l antibody, Spag6 antibody, spag6 antibody, spag6.L antibody

Background:

Synonyms: PF16, PF16 protein homolog, Protein PF16 homolog, Repro SA 1, Repro-SA-1, SPAG6, SPAG6_HUMAN, Sperm associated antigen 6, Sperm flagellar protein, Sperm-associated antigen 6.

Background: The correlation of anti-sperm with cases of unexplained infertility implicates a role for these in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].

Gene ID: 9576

UniProt: O75602