PLAG1 antibody (AA 51-150)

Catalog No. ABIN1714862

Product Details anti-PLAG1 Antibody

Target: PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))

Binding Specificity: AA 51-150

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLAG1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PLAG1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PLAG1

Target: PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))

Alternative Name: PLAG1 (PLAG1 Products)

Synonyms: PLAG1 antibody, MGC152687 antibody, PSA antibody, SGPA antibody, ZNF912 antibody, PLAG1 zinc finger antibody, pleiomorphic adenoma gene 1 antibody, PLAG1 antibody, plag1 antibody, Plag1 antibody

Background:

Synonyms: PSA, SGPA, ZNF912, Zinc finger protein PLAG1, Pleiomorphic adenoma gene 1 protein, PLAG1

Background: Transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. Cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia.

Gene ID: 5324

UniProt: Q6DJT9