GNGT1 antibody (AA 21-70)

Catalog No. ABIN1714814

Product Details anti-GNGT1 Antibody

Target: GNGT1 (G Protein gamma Transducing Activity Polypeptide 1 (GNGT1))

Binding Specificity: AA 21-70

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNGT1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GNGT1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GNGT1

Target: GNGT1 (G Protein gamma Transducing Activity Polypeptide 1 (GNGT1))

Alternative Name: GNGT1 (GNGT1 Products)

Synonyms: GNG1 antibody, G(y)1 antibody, Gng1 antibody, G protein subunit gamma transducin 1 antibody, guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 antibody, GNGT1 antibody, Gngt1 antibody

Background:

Synonyms: G gamma 1, GNG1, GNGT1, Guanine nucleotide binding protein G, Transducin gamma chain, GBG1_HUMAN.

Background: Heterotrimeric guanine nucleotide-binding proteins (G proteins) transduce extracellular signals received by transmembrane receptors to effector proteins. Transducin is a guanine nucleotide-binding protein found specifically in rod outer segments, where it mediates activation by rhodopsin of a cyclic GTP-specific (guanosine monophosphate) phosphodiesterase. Transducin is also referred to as GMPase. GNGT1 encodes the gamma subunit of transducin (Hurley et al., 1984 [PubMed 6438626], Scherer et al., 1996 [PubMed 8661128]).[supplied by OMIM, Mar 2008].

Gene ID: 2792

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction