S100A6 antibody (AA 15-70)

Catalog No. ABIN1714636

Product Details anti-S100A6 Antibody

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Binding Specificity: AA 15-70

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S100A6 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human S100A6

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for S100A6

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Alternative Name: S100A6 (S100A6 Products)

Synonyms: S100A6 antibody, 2A9 antibody, 5B10 antibody, CABP antibody, CACY antibody, PRA antibody, CALCYCLIN antibody, Cacy antibody, S100 calcium binding protein A6 antibody, uncharacterized LOC618256 antibody, S100 calcium binding protein A6 (calcyclin) antibody, S100A6 antibody, S100a6 antibody, LOC618256 antibody

Background:

Synonyms: S100 alpha 6 PRA, Calcyclin, PRAGrowth factor inducible protein 2A9, Prolactin receptor associated protein, Prolactin receptor-associated protein, Protein S100 A6, Protein S100-A6, S100 A6, S100 calcium binding protein A6 calcyclin, S100 calcium binding protein A6, S100 calcium-binding protein A6, S100A6, S100A6_HUMAN, S100-A6, 2A9, 5B10, CABP, CACY, Calcyclin, Growth factor inducible protein 2A9, Growth factor-inducible protein 2A9, MLN 4, MLN4.

Background: Calcyclin, also known as Protein S100-A6, growth factor-inducible protein 2A9, S-100 calcium-binding protein A6 (S-100A6) or MLN 4, is a homodimeric member of the S-100 calcium-binding protein family whose expression is upregulated in proliferating and differentiating cells. Calcyclin is inducible by growth factors and overexpressed in acute myeloid leukemias. It is expressed in a cell-specific manner in subpopulations of neurons and astrocytes and in epithelial cells and fibroblasts. Calcyclin is a specific target of S-100B protein in vivo. The binding of Calcyclin to S-100B is stabilized by S-100B-bound calcium and zinc. Calcyclin associates with both Annexin XI and CacyBP (calcyclin-binding protein). It functions to activate several processes along the calcium signal transduction pathway including the regulation of cell growth, proliferation, secretion and exocytosis.

Gene ID: 10014

Pathways: S100 Proteins