THEMIS antibody (AA 301-400)

Catalog No. ABIN1714633

Product Details anti-THEMIS Antibody

Target: THEMIS (Thymocyte Selection Associated (THEMIS))

Binding Specificity: AA 301-400

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THEMIS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human THEMIS

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for THEMIS

Target: THEMIS (Thymocyte Selection Associated (THEMIS))

Alternative Name: THEMIS (THEMIS Products)

Synonyms: TSEPA antibody, C6orf190 antibody, C6orf207 antibody, GASP antibody, SPOT antibody, bA325O24.3 antibody, bA325O24.4 antibody, A430108D01 antibody, BB160712 antibody, E430004N04Rik antibody, Gasp antibody, Tsepa antibody, thylex antibody, C9H6ORF190 antibody, im:7138580 antibody, tsepa antibody, thymocyte selection associated antibody, THEMIS antibody, Themis antibody, themis antibody

Background:

Synonyms: GASP, SPOT, TSEPA, C6orf190, C6orf207, bA325O24.3, bA325O24.4, Protein THEMIS, Thymocyte-expressed molecule involved in selection, THEMIS

Background: Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk (By similarity).

Gene ID: 387357

UniProt: Q8N1K5