FOXRED1 antibody (AA 251-350)

Catalog No. ABIN1714616

Product Details anti-FOXRED1 Antibody

Target: FOXRED1 (FAD-Dependent Oxidoreductase Domain Containing 1 (FOXRED1))

Binding Specificity: AA 251-350

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXRED1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FOXRED1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FOXRED1

Target: FOXRED1 (FAD-Dependent Oxidoreductase Domain Containing 1 (FOXRED1))

Alternative Name: FOXRED1 (FOXRED1 Products)

Synonyms: H17 antibody, BC024806 antibody, TEG-23 antibody, Tex23 antibody, RGD1311785 antibody, FAD dependent oxidoreductase domain containing 1 antibody, FAD-dependent oxidoreductase domain containing 1 antibody, FOXRED1 antibody, Foxred1 antibody

Background:

Synonyms: FAD dependent oxidoreductase domain containing 1, FAD dependent oxidoreductase domain containing protein 1, FAD-dependent oxidoreductase domain-containing protein 1, FOXRED 1, FOXRED1, FP634, FXRD1_HUMAN, H17.

Background: FOXRED1 is a 486 amino acid single-pass membrane protein. Utilizing FAD as a cofactor, FOXRED1 may act as a chaperone protein essential for the function of mitochondrial complex I. Mutations to FOXRED1 may result in mitochondrial complex I deficiency (MT-C1D), which results in a wide range of clinical maladies from lethal neonatal disease to adult onset neurodegenerative disorders. Common phenotypes of MT-C1D include cardiomyopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. FOXRED1 exists as three alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 11q24.2. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome.

Gene ID: 55572