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CXCR4 antibody (pSer339)

CXCR4 Reactivity: Human, Mouse WB, ELISA, FACS, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1714582
  • Target See all CXCR4 Antibodies
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    Binding Specificity
    • 18
    • 15
    • 15
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer339
    Reactivity
    • 131
    • 83
    • 66
    • 21
    • 11
    • 11
    • 10
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 112
    • 22
    • 10
    • 5
    • 1
    Rabbit
    Clonality
    • 120
    • 30
    Polyclonal
    Conjugate
    • 96
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CXCR4 antibody is un-conjugated
    Application
    • 110
    • 50
    • 45
    • 36
    • 27
    • 26
    • 25
    • 25
    • 18
    • 11
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Rat,Dog,Cow,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human CXCR4 around the phosphorylation site of Ser339 [HS(p-S)VS]
    Isotype
    IgG
    Top Product
    Discover our top product CXCR4 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    Alternative Name
    CXCR4 (CXCR4 Products)
    Background

    Synonyms: p-CXCR4 phospho S339, p-CD184 phospho S339, C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, Stromal cell-derived factor 1 receptor, SDF-1 receptor, Fusin, Leukocyte-derived seven transmembrane domain receptor, LESTR, CD184 antigen, CXCR4_HUMAN.

    Background: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Monomer. Can form dimers.

    Gene ID
    55038
    Pathways
    Regulation of Cell Size, CXCR4-mediated Signaling Events
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