ZBTB43 antibody (AA 351-450)

Catalog No. ABIN1714580

Product Details anti-ZBTB43 Antibody

Target: ZBTB43 (Zinc Finger and BTB Domain Containing 43 (ZBTB43))

Binding Specificity: AA 351-450

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB43 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZBTB43/ZNF297B

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ZBTB43

Target: ZBTB43 (Zinc Finger and BTB Domain Containing 43 (ZBTB43))

Alternative Name: ZBTB43/ZNF297B (ZBTB43 Products)

Synonyms: ZBTB22B antibody, ZNF-X antibody, ZNF297B antibody, 1700010E06Rik antibody, Zfp297b antibody, mKIAA0414 antibody, zinc finger and BTB domain containing 43 antibody, ZBTB43 antibody, Zbtb43 antibody

Background:

Synonyms: RP11489N222, ZBT43_HUMAN, ZBTB22B, ZBTB43, Zinc Finger And BTB Domain Containing 43, Zinc finger and BTB domain-containing protein 22B, Zinc finger and BTB domain-containing protein 43, Zinc Finger Protein 297B, ZnF-x, ZNF297B, ZNFX.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 43 (ZBTB43), also known as ZNF297B or ZBTB22B, is a 467 amino acid member of the Kr_ppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB43 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain and the interaction of ZBTB43 with BDP1 suggest that ZBTB43 functions as a transcription regulator.

Gene ID: 23099