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Glutathione Peroxidase 2 antibody (AA 41-140)

GPX2 Reactivity: Mouse ELISA, WB, ICC, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1714555
  • Target See all Glutathione Peroxidase 2 (GPX2) Antibodies
    Glutathione Peroxidase 2 (GPX2)
    Binding Specificity
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 41-140
    Reactivity
    • 14
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 13
    • 1
    Rabbit
    Clonality
    • 14
    Polyclonal
    Conjugate
    • 10
    • 2
    • 1
    • 1
    This Glutathione Peroxidase 2 antibody is un-conjugated
    Application
    ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GPX2/Glutathione Peroxidase 2
    Isotype
    IgG
    Top Product
    Discover our top product GPX2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    Glutathione Peroxidase 2 (GPX2)
    Alternative Name
    GPX2/Glutathione Peroxidase 2 (GPX2 Products)
    Synonyms
    ATGPX2 antibody, GLUTATHIONE PEROXIDASE antibody, T9H9.9 antibody, T9H9_9 antibody, glutathione peroxidase 2 antibody, GI-GPx antibody, GPRP antibody, GPRP-2 antibody, GPx-2 antibody, GPx-GI antibody, GSHPX-GI antibody, GSHPx-2 antibody, LOC100136264 antibody, GSHPx-GI antibody, GPX-GI antibody, glutathione peroxidase 2 antibody, glutathione peroxidase 1 antibody, GPX2 antibody, gpx1 antibody, Gpx2 antibody, LELG_01052 antibody
    Background

    Synonyms: Gastrointestinal glutathione peroxidase, GI GPx, Glutathione peroxidase 2 gastrointestinal, Glutathione peroxidase 2, Glutathione peroxidase gastrointestinal, Glutathione peroxidase related protein 2, Glutathione peroxidase-gastrointestinal, Glutathione peroxidase-related protein 2, GPRP, GPRP-2, GPx 2, GPx-2, GPx-GI, GPX2, GPX2_HUMAN, GSHPx 2, GSHPx GI, GSHPx-2, GSHPx-GI.

    Background: Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols, and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-18). GPx-1 plays an important role in the antioxidant defense of the vascular wall and neural cells in response to oxidative stress. GPx-2 is the major isoform in the lungs and its basal or inducible expression is dependent on Nrf2. GPx-3 is under regulation by hypoxic stress and the expression and deficiency of GPx-3 is associated with cardiovascular disease and stroke. GPx-5 is selenium-independent, it is bound to the acrosome of sperm, where it may protect sperm from premature acrosome reaction in the epididymis.

    Gene ID
    2877
    Pathways
    Thyroid Hormone Synthesis
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