GCNT1 antibody (AA 201-260)
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- Target See all GCNT1 Antibodies
- GCNT1 (Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1))
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Binding Specificity
- AA 201-260
- Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GCNT1 antibody is un-conjugated
- Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat,Dog,Cow,Sheep
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GCNT1
- Isotype
- IgG
- Top Product
- Discover our top product GCNT1 Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- GCNT1 (Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1))
- Alternative Name
- GCNT1 (GCNT1 Products)
- Synonyms
- C2GNT antibody, C2GNT-L antibody, C2GNT1 antibody, G6NT antibody, NACGT2 antibody, NAGCT2 antibody, 5630400D21Rik antibody, B130048E03 antibody, C2 GlcNAcT antibody, IGnT antibody, core 2 GlcNAc-T antibody, glucosaminyl (N-acetyl) transferase 1, core 2 L homeolog antibody, glucosaminyl (N-acetyl) transferase 1, core 2 antibody, gcnt1.L antibody, GCNT1 antibody, Gcnt1 antibody
- Background
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Synonyms: 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase, Beta-1, Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase, C2GNT, C2GNT L, C2GNT1, C2GnTL, Core 2 branching enzyme, Core 2 GNT, Core 2-branching enzyme, Core2 GlcNAc transferase, Core2-GlcNAc-transferase, GCNT 1, GCNT 1, GCNT1, GCNT1_HUMAN, glucosaminyl N-acetyl transferase 1 core 2, NACGT2.
Background: GCNT1 is expressed in a variety of cell types, including lymphocytes and mucin-producing cells. Specifically, GCNT1 expression in leukocytes regulates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectins. Downregulation of Selectin ligand expression levels has been shown to inhibit tissue infiltration. Therefore, GCNT1 represents a potential drug target for the treatment of inflammatory disorders and other pathologies involving Selectins.
- Gene ID
- 2650
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