BANF1 antibody (AA 21-89)

Catalog No. ABIN1714491

Product Details anti-BANF1 Antibody

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Binding Specificity: AA 21-89

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BANF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BANF1/BAF

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for BANF1

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Alternative Name: BANF1/BAF (BANF1 Products)

Synonyms: BAF antibody, BCRP1 antibody, D14S1460 antibody, NGPS antibody, Baf antibody, Bcrp1 antibody, L2bp1 antibody, L2bp1/Baf antibody, BANF1 antibody, DKFZp468C097 antibody, C78287 antibody, baf antibody, bcrp1 antibody, fa01c01 antibody, wu:fa01c01 antibody, zgc:77767 antibody, CG7380 antibody, Dmel\\CG7380 antibody, anon-WO0172774.178 antibody, dBAF antibody, banf1 antibody, banf1-a antibody, banf1-b antibody, barrier to autointegration factor 1 antibody, barrier to autointegration factor 1 pseudogene antibody, barrier to autointegration factor antibody, barrier to autointegration factor 1 S homeolog antibody, BANF1 antibody, Banf1 antibody, banf1 antibody, LOC100397017 antibody, baf antibody, banf1.S antibody

Background:

Synonyms: BAF, BAF_HUMAN, BANF 1, BANF1, Barrier to autointegration factor 1, Barrier to autointegration factor, Barrier-to-autointegration factor, BCRG 1, BCRG1, BCRP 1, BCRP1, Breakpoint cluster region protein 1, D14S1460, MGC111161.

Background: Barrier-to-autointegration factor (BAF) binds non-specifically to double stranded DNA, possibly to play a role in tissue- or cell type-specific gene expression by interacting with different homeodomain transcription factors. BAF compresses chromatin structure and interacts with the LEM domain of nuclear proteins to play a crucial role in membrane recruitment and chromatin decondensation during nuclear assembly. Additionally, retroviruses like HIV-1 incorporate BAF from host cells into preintegration complexes (PICs) to prevent autointegration of retroviral DNA and thereby promote integration of retroviral DNA into the host chromosome.

Gene ID: 8815