HCCS antibody (AA 51-150)

Catalog No. ABIN1714466

Product Details anti-HCCS Antibody

Target: HCCS (Holocytochrome C Synthase (HCCS))

Binding Specificity: AA 51-150

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCCS antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HCCS

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for HCCS

Target: HCCS (Holocytochrome C Synthase (HCCS))

Alternative Name: HCCS (HCCS Products)

Synonyms: hccsb antibody, id:ibd1278 antibody, wu:fb18h01 antibody, wu:fc64e12 antibody, wu:fi43e01 antibody, cchl antibody, mcops7 antibody, DDBDRAFT_0217711 antibody, DDBDRAFT_0266707 antibody, DDB_0217711 antibody, DDB_0266707 antibody, CCHL antibody, MCOPS7 antibody, RGD1563855 antibody, holocytochrome c synthase b antibody, holocytochrome c synthase antibody, cytochrome c heme-lyase antibody, cytochrome c-type heme lyase antibody, holocytochrome c synthetase antibody, hccsb antibody, hccs antibody, cchl antibody, HCCS antibody, Hccs antibody, LOC100356413 antibody

Background:

Synonyms: CCHL, DKFZp779I1858, EC 4.4.1.17, Holocytochrome c synthase cytochrome c heme lyase, Holocytochrome c type synthase, MCOPS7, OTTHUMP00000022903, OTTHUMP00000022904, OTTHUMP00000022905, OTTMUSP00000021173, OTTMUSP00000021174, RGD1563855, RP23-37L2.1, CCHL_HUMAN.

Background: HCCS is a 79 amino acid protein that may act as a tumor suppressor, promoting the apoptosis of cancer cells. Expressed in leukocytes, lung, spleen, liver, heart, kidney, muscle and uterine cervix, HCCS-1 is down-regulated in cervical cancers. The gene encoding HCCS-1 maps to human chromosome 15q25.1. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and comprises about 3 % of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.

Gene ID: 3052

UniProt: P53701