GNPTG antibody (AA 41-140)

Catalog No. ABIN1714463

Product Details anti-GNPTG Antibody

Target: GNPTG (N-Acetylglucosamine-1-Phosphate Transferase, gamma Subunit (GNPTG))

Binding Specificity: AA 41-140

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNPTG antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GNPTG

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GNPTG

Target: GNPTG (N-Acetylglucosamine-1-Phosphate Transferase, gamma Subunit (GNPTG))

Alternative Name: GNPTG (GNPTG Products)

Background:

Synonyms: GlcNAc phosphotransferase gamma subunit, GlcNAc-1-phosphotransferase subunit gamma, GNPTAG, LP2537, N-acetylglucosamine-1-phosphate transferase gamma subunit, RJD9, UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma, GNPTG_HUMAN.

Background: This gene encodes the gamma sunbunit of the N-acetylglucosamine-1-phosphotransferase complex. This hexameric complex, composed of alpha, beta and gamma subunits, catalyzes the first step in synthesis of a mannose 6-phosphate lysosomal recognition marker. This enzyme complex is necessary for targeting of lysosomal hydrolases to the lysosome. Mutations in the gene encoding the gamma subunit have been associated with mucolipidosis IIIC, also known as mucolipidosis III gamma.[provided by RefSeq, Feb 2010].

Gene ID: 84572