FPGS antibody (AA 51-150)

Catalog No. ABIN1714446

Product Details anti-FPGS Antibody

Target: FPGS (Folylpolyglutamate Synthase (FPGS))

Binding Specificity: AA 51-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FPGS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FPGS/Folylpolyglutamate synthase

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FPGS

Target: FPGS (Folylpolyglutamate Synthase (FPGS))

Alternative Name: FPGS/Folylpolyglutamate synthase (FPGS Products)

Synonyms: zgc:63807 antibody, wu:fk49h03 antibody, wu:fk51d09 antibody, FPGS antibody, fpgS antibody, SCC88.25c antibody, BA4689 antibody, AA408187 antibody, folylpolyglutamate synthase antibody, dihydrofolate synthase antibody, folylpolyglutamate synthase, mitochondrial antibody, folylpolyglutamyl synthetase antibody, fpgs antibody, fpgS antibody, FPGS antibody, SCO2614 antibody, fgs antibody, folC antibody, CpipJ_CPIJ008043 antibody, Fpgs antibody

Background:

Synonyms: EC 6.3.2.17, FOLC, FOLC_HUMAN, Folylpoly gamma glutamate synthetase, Folylpoly-gamma-glutamate synthetase, Folylpolyglutamate synthase, Folylpolyglutamate synthase mitochondrial, FPGS, mitochondrial, OTTHUMP00000022201, OTTHUMP00000022202, Tetrahydrofolate synthase, Tetrahydrofolylpolyglutamate synthase.

Background: This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq, Jul 2008].

Gene ID: 2356