Glutathione Peroxidase 7 antibody (AA 11-110)

Catalog No. ABIN1714004

Product Details anti-Glutathione Peroxidase 7 Antibody

Target: Glutathione Peroxidase 7 (GPX7)

Binding Specificity: AA 11-110

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutathione Peroxidase 7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Chicken,Rabbit,Monkey

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPX7/Glutathione Peroxidase 7

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Glutathione Peroxidase 7

Target: Glutathione Peroxidase 7 (GPX7)

Alternative Name: GPX7/Glutathione Peroxidase 7 (GPX7 Products)

Background:

Synonyms: CL683, FLJ14777, Glutathione peroxidase 7, GPx-7, GPX6, GPX7, GPX7_HUMAN, GSHPx-7, NPGPx.

Background: Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-18). GPx-7 (glutathione peroxidase 7), also known as GPX6, CL683 or NPGPx, is a 187 amino acid secreted protein belonging to the glutathione peroxidase family. GPx-7 catalyzes the reaction of glutathione into glutathione disulfide and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome.

Gene ID: 2882

Pathways: Thyroid Hormone Synthesis