GNG5 antibody (AA 21-65)

Catalog No. ABIN1714003

Product Details anti-GNG5 Antibody

Target: GNG5 (G Protein gamma 5 (GNG5))

Binding Specificity: AA 21-65

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNG5 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GNG5

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GNG5

Target: GNG5 (G Protein gamma 5 (GNG5))

Alternative Name: GNG5 (GNG5 Products)

Synonyms: G(y)5 antibody, G protein subunit gamma 5 antibody, guanine nucleotide binding protein (G protein), gamma 5 antibody, Gng5 antibody, GNG5 antibody

Background:

Synonyms: FLJ92393, GBG5_HUMAN, Gng5, Guanine nucleotide-binding protein GI/GS/GO subunit gamma-5, OTTHUMP00000011474, OTTHUMP00000011565.

Background: Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (i.e. a photon, pheromone, odorant, hormone or neurotransmitter), while the effectors (e.g. adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alhfa, beta and gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their a subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Evidence, however, has established an important regulatory role for the beta gamma subunits. It is becoming increasingly clear that different G protein complexes expressed in different tissues carry structurally distinct members of the gamma as well as the alhfa and beta subunits, and that preferential associations between members of subunit families increase G protein functional diversity.

Gene ID: 2787

Pathways: Myometrial Relaxation and Contraction, SARS-CoV-2 Protein Interactome