GBAS antibody (AA 21-120)

Catalog No. ABIN1714000

Product Details anti-GBAS Antibody

Target: GBAS (Glioblastoma Amplified Sequence (GBAS))

Binding Specificity: AA 21-120

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBAS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GBAS

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GBAS

Target: GBAS (Glioblastoma Amplified Sequence (GBAS))

Alternative Name: GBAS (GBAS Products)

Synonyms: nipsnap2 antibody, wu:fc08b08 antibody, zgc:92497 antibody, NIPSNAP2 antibody, AV006093 antibody, Nipsnap2 antibody, nipsnap homolog 2 antibody, glioblastoma amplified sequence antibody, nipsnap2 antibody, NIPSNAP2 antibody, GBAS antibody, Nipsnap2 antibody

Background:

Synonyms: 4 nitrophenylphosphatase domain and non neuronal SNAP25 like 2, gbas, Glioblastoma amplied sequence, Glioblastoma-amplied sequence, NIPS2_HUMAN, Nipsnap homolog 2, NipSnap2, Protein NipSnap homolog 2.

Background: NIPSNAP2 is a 286 amino acid protein that is abundantly expressed in heart and skeletal muscle. Belonging to the NIPSNAP family, NIPSNAP2 may be involved in vesicular transport. NIPSNAP2 contains a signal peptide, a transmembrane domain and two tyrosine phosphorylation sites. NIPSNAP2 is encoded by a gene mapping to human chromosome 7p11.2. Chromosomal region 7p12 is amplified in approximately 40 % of glioblastomas, the most common and malignant form of central nervous system tumor. Human chromosome 7 houses over 1,000 genes and comprises nearly 5 % of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Gene ID: 2631

Pathways: Ribonucleoside Biosynthetic Process