Ectodysplasin A antibody (AA 101-200)

Catalog No. ABIN1713994

Product Details anti-Ectodysplasin A Antibody

Target: Ectodysplasin A (EDA)

Binding Specificity: AA 101-200

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ectodysplasin A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Ectodysplasin-A, membrane form/secreted form

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Ectodysplasin A antibody (ABIN1713994)

Sisto, Barca, Lofrumento, Lisi: "Downstream activation of NF-κB in the EDA-A1/EDAR signalling in Sjögren's syndrome and its regulation by the ubiquitin-editing enzyme A20." in: Clinical and experimental immunology, Vol. 184, Issue 2, pp. 183-96, (2016) (PubMed).

Target Details for Ectodysplasin A

Target: Ectodysplasin A (EDA)

Alternative Name: EDA/Ectodermal dysplasia protein (EDA Products)

Synonyms: ECTD1 antibody, ED1 antibody, ED1-A1 antibody, ED1-A2 antibody, EDA-A1 antibody, EDA-A2 antibody, EDA1 antibody, EDA2 antibody, HED antibody, HED1 antibody, ODT1 antibody, STHAGX1 antibody, XHED antibody, XLHED antibody, si:ch73-223d24.5 antibody, Ed1 antibody, Eda-A1 antibody, Eda-A2 antibody, Ta antibody, tabby antibody, RGD1563178 antibody, ectodysplasin A antibody, ectodysplasin-A antibody, EDA antibody, eda antibody, Eda antibody

Background:

Synonyms: ED1, HED, EDA1, EDA2, HED1, ODT1, XHED, ECTD1, XLHED, ED1-A1, ED1-A2, EDA-A1, EDA-A2, TNLG7C, STHAGX1, Ectodysplasin-A, Ectodermal dysplasia protein, EDA protein, EDA

Background: Seems to be involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Isoform 1 binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor XEDAR.

Gene ID: 1896

UniProt: Q92838

Pathways: Tube Formation