m1ip1 antibody (AA 21-120)

Catalog No. ABIN1713900

Product Details anti-m1ip1 Antibody

Target: m1ip1 (Mid1-Interacting Protein 1 (m1ip1))

Binding Specificity: AA 21-120

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This m1ip1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLAP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for m1ip1

Target: m1ip1 (Mid1-Interacting Protein 1 (m1ip1))

Alternative Name: SLAP (m1ip1 Products)

Synonyms: MIG12 antibody, TB10 antibody, G12-like antibody, S14R antibody, STRAIT11499 antibody, THRSPL antibody, 3110038L01Rik antibody, Mig12 antibody, slap antibody, mig12 antibody, thrspl antibody, MGC80850 antibody, zgc:73223 antibody, g12 antibody, wu:fj32f05 antibody, thymosin beta 10 antibody, MID1 interacting protein 1 antibody, Mid1-interacting protein 1 antibody, Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish)) antibody, MID1 interacting protein 1 S homeolog antibody, MID1 interacting protein 1b antibody, MID1 interacting protein 1a antibody, TMSB10 antibody, MID1IP1 antibody, m1ip1 antibody, Mid1ip1 antibody, mid1ip1.S antibody, mid1ip1b antibody, mid1ip1a antibody

Background:

Synonyms: hSLAP, SLA 1, SLA, SLA1, SLAP 1, SLAP, SLAP-1, SLAP1, SLAP1_HUMAN, Src like adapter, Src like adapter protein 1, Src like adaptor, SRC-like-adapter, Src-like-adapter protein 1.

Background: The Src homology 3 (SH3) region is a small protein domain of approximately 60 amino acids present in a large group of proteins. In general, it exists in association with catalytic domains, as in the nonreceptor protein-tyrosine kinases and phospholipase C-? within structural proteins, such as spectrin or Myosin, and in small adapter proteins, such as Crk and GRB2. SH3 domains are often accompanied by SH2 domains of 100 amino acids, which bind to tyrosine-phosphorylated regions of target proteins, frequently linking activated growth factors to putative signal transduction proteins. The functions of SH3 domains are not as well defined. Deletion or mutation of SH3 domains generally activate the transforming potential of nonreceptor tyrosine kinases, suggesting that SH3 mediates negative regulation of an intrinsic transforming activity. 3BP1 has been identified as a protein with a high affinity proline-rich binding site for the SH3 domain of c-Abl p120. A similar putative adapter protein, designated Slap, for Src-like adapter protein, has been cloned. Slap contains a single SH2 and SH3 domain that exhibits homology with those from members of the Src kinase family. The N- and C-termini, however, are unique.