PRG2 antibody (AA 51-150)

Catalog No. ABIN1713886

Product Details anti-PRG2 Antibody

Target: PRG2 (Bone Marrow Proteoglycan (PRG2))

Binding Specificity: AA 51-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRG2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PRG2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PRG2

Target: PRG2 (Bone Marrow Proteoglycan (PRG2))

Alternative Name: PRG2 (PRG2 Products)

Synonyms: MBP antibody, mMBP antibody, mMBP-1 antibody, BMPG antibody, MBP1 antibody, proteoglycan 2, bone marrow antibody, proteoglycan 2 antibody, proteoglycan 2, pro eosinophil major basic protein antibody, Prg2 antibody, PRG2 antibody

Background:

Synonyms: BMPG, EMBP, Eosinophil granule major basic protein, Eosinophil major basic protein, MBP, MBP1, Natural killer cell activator, Pregnancy-associated major basic protein, PRG 2, PRG2, PRG2_HUMAN, Proteoglycan 2, Proteoglycan 2 bone marrow, Proteoglycan 2 preproprotein.

Background: The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].

Gene ID: 5553

UniProt: P13727