PIK3AP1 antibody (AA 601-700)

Catalog No. ABIN1713881

Product Details anti-PIK3AP1 Antibody

Target: PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))

Binding Specificity: AA 601-700

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIK3AP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PIK3AP1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PIK3AP1

Target: PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))

Alternative Name: PIK3AP1 (PIK3AP1 Products)

Synonyms: BCAP antibody, RP11-34E5.3 antibody, 1810044J04Rik antibody, phosphoinositide-3-kinase adaptor protein 1 antibody, PIK3AP1 antibody, Pik3ap1 antibody

Background:

Synonyms: B cell adaptor protein, B-cell adapter for phosphoinositide 3-kinase, B-cell phosphoinositide 3-kinase adapter protein 1, BCAP, BCAP_HUMAN, OTTHUMP00000020175, OTTHUMP00000020176, Phosphoinositide 3 kinase adaptor protein 1, Phosphoinositide 3-kinase adapter protein 1, PIK3AP1, RP11-34E5.3.

Background: B cell adaptor for phosphoinositide 3-kinase (BCAP) is a tyrosine kinase substrate that bridges B cell receptor (BCR) associated kinases to the PIK3 pathway. Syk, Btk or Lyn-dependent tyrosine phosphorylation of BCAP, provides binding sites for the p85 subunit of PIK3. BCAP mRNA is present in mouse spleen, thymus, liver, lung, macrophage and B cell lines. Human BCAP maps to chromosome 10q24.2.

Pathways: Activation of Innate immune Response, BCR Signaling, Warburg Effect