MHC Class II antibody (AA 111-200)
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- Target See all MHC Class II (MHC2) Antibodies
- MHC Class II (MHC2) (Major Histocompatibility Complex Class II Antigen (MHC2))
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Binding Specificity
- AA 111-200
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Reactivity
- Mouse, Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MHC Class II antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunocytochemistry (ICC)
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human HLA class II histocompatibility antigen DM beta chain
- Isotype
- IgG
- Top Product
- Discover our top product MHC2 Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- MHC Class II (MHC2) (Major Histocompatibility Complex Class II Antigen (MHC2))
- Alternative Name
- MHC Class II (MHC2 Products)
- Synonyms
- H-2 antibody, MHC-II antibody, histocompatibility-2, MHC antibody, H2 antibody
- Background
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Synonyms: RING7, D6S221E, HLA class II histocompatibility antigen, DM beta chain, MHC class II antigen DMB, Really interesting new gene 7 protein, HLA-DMB, DMB
Background: Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.
- Gene ID
- 3109
- UniProt
- P28068
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