C1orf159 antibody (AA 121-220)

Catalog No. ABIN1713715

Product Details anti-C1orf159 Antibody

Target: C1orf159 (Chromosome 1 Open Reading Frame 159 (C1orf159))

Binding Specificity: AA 121-220

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1orf159 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf159

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C1orf159

Target: C1orf159 (Chromosome 1 Open Reading Frame 159 (C1orf159))

Alternative Name: C1orf159 (C1orf159 Products)

Synonyms: DKFZp459M0116 antibody, chromosome 21 C1orf159 homolog antibody, chromosome 1 open reading frame 159 antibody, chromosome 1 open reading frame, human C1orf159 antibody, C21H1orf159 antibody, c1orf159 antibody, C1H1orf159 antibody, C1orf159 antibody

Background:

Synonyms: Chromosome 1 open reading frame 159, FLJ20584, FLJ21143, FLJ36119, Hypothetical protein LOC54991, OTTHUMP00000000896, OTTHUMP00000044090, RP11-465B22.4, Uncharacterized protein C1orf159, CA159_HUMAN.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf159 gene product has been provisionally designated C1orf159 pending further characterization.

Gene ID: 54991