HERC4 antibody (AA 301-400)

Catalog No. ABIN1713665

Product Details anti-HERC4 Antibody

Target: HERC4 (Hect Domain and RLD 4 (HERC4))

Binding Specificity: AA 301-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HERC4 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HERC4

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for HERC4

Target: HERC4 (Hect Domain and RLD 4 (HERC4))

Alternative Name: HERC4 (HERC4 Products)

Synonyms: 1700056O17Rik antibody, 4921531D01Rik antibody, 9530080M15Rik antibody, mKIAA1593 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 4 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 4 S homeolog antibody, hect domain and RLD 4 antibody, HERC4 antibody, herc4 antibody, herc4.S antibody, Herc4 antibody

Background:

Synonyms: DKFZP564G092, HECT and RLD domain containing E3 ubiquitin protein ligase 4, HECT domain and RCC1 like domain containing protein 4, HECT domain and RCC1-like domain-containing protein 4, Hect domain and RLD 4, HERC 4, HERC4, HERC4_HUMAN, KIAA1593, Probable E3 ubiquitin protein ligase HERC4, Probable E3 ubiquitin-protein ligase HERC4.

Background: HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).

Gene ID: 26091