GPR146 antibody (AA 221-320)

Catalog No. ABIN1713498

Product Details anti-GPR146 Antibody

Target: GPR146 (G Protein-Coupled Receptor 146 (GPR146))

Binding Specificity: AA 221-320

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR146 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human G protein coupled receptor 146

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GPR146

Target: GPR146 (G Protein-Coupled Receptor 146 (GPR146))

Alternative Name: GPR146 (GPR146 Products)

Synonyms: GPR146 antibody, zgc:153785 antibody, PGR8 antibody, BC003323 antibody, RGD1560731 antibody, G protein-coupled receptor 146 antibody, G protein-coupled receptor 146 L homeolog antibody, GPR146 antibody, gpr146 antibody, Gpr146 antibody, gpr146.L antibody

Background:

Synonyms: G protein coupled receptor 146, G-protein coupled receptor PGR8, GP146_HUMAN, GPR146, PGR8, Probable G-protein coupled receptor 146, GPCR GPR146.

Background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR146 (G protein-coupled receptor 146), also known as PGR8, is a 333 amino acid multi-pass transmembrane protein that belongs to the G-protein coupled receptor 1 family. Characterized as an orphan receptor for which its endogenous ligand has yet to be identified, GPR146 is thought to play a role in signaling events throughout the cell.

Gene ID: 115330

UniProt: Q96CH1