RNASE3 antibody (AA 45-160)

Catalog No. ABIN1713488

Product Details anti-RNASE3 Antibody

Target: RNASE3 (ECP) (Eosinophil Cationic Protein (ECP))

Binding Specificity: AA 45-160

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASE3 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ECP

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-RNASE3 antibody (ABIN1713488)

Inada, Shoji, Shiraki, Aso, Yamagami: "Histamine H1 and H4 receptor expression on the ocular surface of patients with chronic allergic conjunctival diseases." in: Allergology international : official journal of the Japanese Society of Allergology, (2017) (PubMed).

Tokunaga, Ninomiya, Kato, Imoto, Sakashita, Takabayashi, Noguchi, Fujieda: "The significant expression of TRPV3 in nasal polyps of eosinophilic chronic rhinosinusitis." in: Allergology international : official journal of the Japanese Society of Allergology, (2017) (PubMed).

Fujisawa, Kashiwakura, Kita, Kikukawa, Fujitani, Sasaki-Sakamoto, Kuroda, Nunomura, Hayama, Terui, Ra, Okayama: "Expression of Mas-related gene X2 on mast cells is upregulated in the skin of patients with severe chronic urticaria." in: The Journal of allergy and clinical immunology, Vol. 134, Issue 3, pp. 622-633.e9, (2014) (PubMed).

Target Details for RNASE3

Target: RNASE3 (ECP) (Eosinophil Cationic Protein (ECP))

Alternative Name: ECP (ECP Products)

Synonyms: ECP antibody, RNS3 antibody, ribonuclease A family member 3 antibody, RNASE3 antibody

Background:

Synonyms: ECP, RNS3, Eosinophil cationic protein, Ribonuclease 3, RNase 3, RNASE3

Background: Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.

Gene ID: 6037

UniProt: P12724