IFITM5 antibody (PE-Cy5)

Catalog No. ABIN1712946

Product Details anti-IFITM5 Antibody (PE-Cy5)

Target: IFITM5 (Interferon Induced Transmembrane Protein 5 (IFITM5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFITM5 antibody is conjugated to PE-Cy5

Application: Western Blotting (WB)

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IFITM5

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IFITM5

Target: IFITM5 (Interferon Induced Transmembrane Protein 5 (IFITM5))

Alternative Name: IFITM5 (IFITM5 Products)

Synonyms: BRIL antibody, DSPA1 antibody, Hrmp1 antibody, OI5 antibody, fragilis4 antibody, 1110003J06Rik antibody, AW213665 antibody, Bril antibody, Hrtm1 antibody, interferon induced transmembrane protein 5 antibody, interferon-induced transmembrane protein 1 antibody, Ifitm5 antibody, IFITM5 antibody, LOC606890 antibody

Background:

Synonyms: Bone-restricted interferon-induced transmembrane protein-like protein, BRIL, Fragilis4, Hrmp1, ITM5, M5_HUMAN, Interferon-induced transmembrane protein 5.

Background: IFITM5 is a membrane protein thought to play a role in bone mineralization. This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195).