GMPPB antibody (AA 111-210) (HRP)
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- Target See all GMPPB Antibodies
- GMPPB (GDP-Mannose Pyrophosphorylase B (GMPPB))
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Binding Specificity
- AA 111-210
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GMPPB antibody is conjugated to HRP
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Predicted Reactivity
- Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GMPPB
- Isotype
- IgG
- Top Product
- Discover our top product GMPPB Primary Antibody
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- Application Notes
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- GMPPB (GDP-Mannose Pyrophosphorylase B (GMPPB))
- Alternative Name
- GMPPB (GMPPB Products)
- Synonyms
- MDDGA14 antibody, MDDGB14 antibody, MDDGC14 antibody, AI317178 antibody, E430010H19 antibody, RGD1560458 antibody, gmppl antibody, zgc:92026 antibody, GMPPB antibody, gmppb antibody, gmppb-a antibody, gmppb-b antibody, GDP-mannose pyrophosphorylase B antibody, GDP-mannose pyrophosphorylase B L homeolog antibody, GDP-mannose pyrophosphorylase B S homeolog antibody, GMPPB antibody, Gmppb antibody, gmppb antibody, LOAG_13550 antibody, gmppb.L antibody, gmppb.S antibody
- Background
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Synonyms: GDP mannose pyrophosphorylase B, GDP-mannose pyrophosphorylase B, GMPPB, GMPPB_HUMAN, GTP-mannose-1-phosphate guanylyltransferase beta, KIAA1851, Mannose 1 phosphate guanylyltransferase, Mannose-1-phosphate guanyltransferase beta.
Background: GMPPB is a 360 amino acid protein that belongs to the transferase hexapeptide repeat family and is involved in protein modification pathways. Functioning as a GDP-mannose pyrophosphorylase, GMPPB enzymatically catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose and a free phosphate, a reaction that is involved in the production of N-linked oligosaccharides. Defects in the gene encoding GMPPB that cause errors in the glycosylation pathway may lead to congenital disorders of glycosylation (CDG). CDGs are multisystemic diseases that often involve both the central and peripheral nervous systems and are often characterized by endocrine and coagulation disorders. GMPPB is expressed as two isoforms due to alternative splicing events.
- Gene ID
- 29925
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