CACFD1 antibody (AA 41-130) (HRP)

Catalog No. ABIN1712123

Product Details anti-CACFD1 Antibody (HRP)

Target: CACFD1 (Calcium Channel Flower Domain Containing 1 (CACFD1))

Binding Specificity: AA 41-130

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACFD1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C9orf7

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CACFD1

Target: CACFD1 (Calcium Channel Flower Domain Containing 1 (CACFD1))

Alternative Name: C9orf7 (CACFD1 Products)

Synonyms: C9orf7 antibody, D9S2135 antibody, FLOWER antibody, 5930434B04Rik antibody, mFwe antibody, calcium channel flower domain containing 1 antibody, CACFD1 antibody, Cacfd1 antibody

Background:

Synonyms: C9orf7, Calcium channel flower homolog, Chromosome 9 open reading frame 7, D9S2135, FLOWR_HUMAN, RP13-100B2.5.

Background: Chromosome 9 consists of about 145 million bases and 4 % of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The C9orf7 gene product has been provisionally designated C9orf7 pending further characterization.

Gene ID: 11094