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PTCHD2 antibody (AA 401-500) (HRP)

PTCHD2 Reactivity: Human WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal HRP
Catalog No. ABIN1711738
  • Target See all PTCHD2 Antibodies
    PTCHD2 (Patched Domain Containing 2 (PTCHD2))
    Binding Specificity
    • 14
    • 9
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 401-500
    Reactivity
    • 38
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    Human
    Host
    • 38
    Rabbit
    Clonality
    • 38
    Polyclonal
    Conjugate
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTCHD2 antibody is conjugated to HRP
    Application
    • 34
    • 18
    • 13
    • 13
    • 7
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PTCHD2/DISP3
    Isotype
    IgG
    Top Product
    Discover our top product PTCHD2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PTCHD2 (Patched Domain Containing 2 (PTCHD2))
    Alternative Name
    PTCHD2/DISP3 (PTCHD2 Products)
    Synonyms
    DISP3 antibody, G630052C06Rik antibody, RNDEu-2 antibody, RGD1305820 antibody, dispatched RND transporter family member 3 antibody, patched domain-containing protein 2 antibody, si:dkey-32e23.6 antibody, DISP3 antibody, LOC100082708 antibody, si:dkey-32e23.6 antibody, disp3 antibody, Disp3 antibody
    Background

    Synonyms: DISP3, Dispatched, drosophila, homolog of, 3, G630052C06Rik, hCG_24779, KIAA1337, Patched domain-containing protein 2, Protein dispatched homolog 3, Ptchd2, PTHD2_HUMAN, RGD1305820, RND-type protein RNDEu-2, RNDEu-2, patched domain containing 2, RP23-157B15.1.

    Background: PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.

    Gene ID
    57540
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