ZSCAN10 antibody (AA 551-650) (HRP)

Catalog No. ABIN1711186

Product Details anti-ZSCAN10 Antibody (HRP)

Target: ZSCAN10 (Zinc Finger and SCAN Domain Containing 10 (ZSCAN10))

Binding Specificity: AA 551-650

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZSCAN10 antibody is conjugated to HRP

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZNF206

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ZSCAN10

Target: ZSCAN10 (Zinc Finger and SCAN Domain Containing 10 (ZSCAN10))

Alternative Name: ZNF206 (ZSCAN10 Products)

Synonyms: ZNF206 antibody, BC068284 antibody, Zfp206 antibody, Zkscan10 antibody, Znf206 antibody, zinc finger and SCAN domain containing 10 antibody, ZSCAN10 antibody, Zscan10 antibody

Background:

Synonyms: Zfp206, Zinc finger and SCAN domain-containing protein 10, Zinc Finger Protein 206, ZSCAN10.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF206 (zinc finger protein 206), also known as ZSCAN10 (zinc finger and SCAN domain containing 10), is a 725 amino acid protein that contains one SCAN box domain and 14 C2H2-type zinc fingers. Localized to the nucleus, ZNF206 is thought to play a role in transcriptional regulation events. The gene encoding ZNF206 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.