HERC2 antibody (AA 51-200) (HRP)

Catalog No. ABIN1711045

Product Details anti-HERC2 Antibody (HRP)

Target: HERC2 (Hect Domain and RLD 2 (HERC2))

Binding Specificity: AA 51-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HERC2 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HERC2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HERC2

Target: HERC2 (Hect Domain and RLD 2 (HERC2))

Alternative Name: HERC2 (HERC2 Products)

Synonyms: CG11734 antibody, Dmel\\CG11734 antibody, D15F32S1h antibody, D7H15F32S1 antibody, D7H15F37S1 antibody, jdf2 antibody, mKIAA0393 antibody, rjs antibody, D15F37S1 antibody, SHEP1 antibody, p528 antibody, HECT and RLD domain containing protein 2 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 2 antibody, HERC2 antibody, Herc2 antibody

Background:

Synonyms: HECT domain and RCC1 like domain containing protein 2, Hect domain and RLD 2, jdf2, p528, SHEP1, HERC2_HUMAN, E3 ubiquitin-protein ligase HERC2, HECT-type E3 ubiquitin transferase HERC2

Background: HERC2 is a belongs to the HERC gene family that encodes a group of unusually large proteins, which contain multiple structural domains. All members have at least 1 copy of an N-terminal region showing homology to the cell cycle regulator RCC1 and a C-terminal HECT (homologous to E6-AP C terminus) domain found in a number of E3 ubiquitin protein ligases. Genetic variations in this gene are associated with skin/hair/eye pigmentation variability. Multiple pseudogenes of this gene are located on chromosomes 15 and 16.

Gene ID: 8924

UniProt: O95714