GGNBP1 antibody (AA 25-109) (HRP)

Catalog No. ABIN1711021

Product Details anti-GGNBP1 Antibody (HRP)

Target: GGNBP1 (Gametogenetin Binding Protein 1 (GGNBP1))

Binding Specificity: AA 25-109

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGNBP1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GGNBP1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GGNBP1

Target: GGNBP1 (Gametogenetin Binding Protein 1 (GGNBP1))

Alternative Name: GGNBP1 (GGNBP1 Products)

Synonyms: 0610031G08Rik antibody, mdf antibody, GGNBP1 antibody, gametogenetin binding protein 1 antibody, gametogenetin binding protein 1 (pseudogene) antibody, gametogenetin-binding protein 1-like antibody, Ggnbp1 antibody, GGNBP1 antibody, LOC516410 antibody

Background:

Synonyms: Gametogenetin-binding protein 1, GGNBP1, Putative gametogenetin-binding protein 1, GGNB1_HUMAN.

Background: GGNBP1 is a 109 amino acid protein that is thought to be involved in spermatogenesis and interacts with gametogenetin. GGNBP1 localizes to cytoplasm, membrane and Golgi apparatus, and exits as two isoforms which are produced by alternative splicing events. The gene encoding GGNBP1 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6 % of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.